Arnold Hilgers Institute
News - Gesamtübersicht
Virus 'link' to childhood obesity
2010-09-20 12:37 (0 Kommentare)
bbc.co.uk:
A virus which causes respiratory infections has been linked to childhood obesity, in a study that is likely to reignite a controversial debate.
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Scientists Discover Gene Mutation Common in a Class of Ovarian Cancers
2010-09-08 10:48 (0 Kommentare)
hhmi.org:
Discovery Provides Strong Link between Genetics and Epigenetics of Cancer
A study of aggressive ovarian tumors has revealed a new class of major cancer-driving mutations. Howard Hughes Medical Institute (HHMI) researchers found that most of the clear cell ovarian carcinoma samples they studied carried a gene mutation that alters the epigenetics of cells.
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Study shows ME/CFS 'virus link' found in children
2010-09-07 09:32 (0 Kommentare)
bbc.co.uk:
A study on children has found further evidence that ME, or Chronic Fatigue Syndrome, could be caused by a virus.
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Why Fish Oils Work Swimmingly Against Inflammation and Diabetes
2010-09-04 16:52 (0 Kommentare)
sciencedaily.com:
Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance.
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Use the Common Cold Virus to Target and Disrupt Cancer Cells?
2010-08-26 15:01 (0 Kommentare)
sciencedaily.com:
A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted cancer therapy, report researchers at the Salk Institute for Biological Studies in the Aug. 26, 2010 issue of Nature.
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Inflammation in Carcinogenesis
2010-06-24 12:12 (0 Kommentare)
sciencedirect.com:
Although inflammation is primarily a homeostatic response of tissues to damage by infectious, physical, or chemical agents, its persistence in a chronic form generates a profoundly modified environment that favors the occurrence of transformed cells and their progression to malignant cancer. Chronic inflammation is one of the hallmarks of most solid tumors and is a precursor condition in a wide range of pathologies including cancers of the colon, esophagus, stomach, or bladder.
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Vitamin D Deficiency as a Risk Factor for Multiple Sclerosis
2010-06-15 11:52 (0 Kommentare)
rndsystems.com:
Multiple sclerosis (MS) is an autoimmune neurological disorder that affects over 2 million people worldwide. Onset of the disease is thought to occur following exposure of genetically predisposed individuals to an unknown environmental trigger that activates myelin-specific T cells. These cells cross the blood-brain barrier to trigger an inflammatory attack that demyelinates axons in the central nervous system. Polymorphisms in the vitamin D receptor are among the genetic variations that increase the risk of MS. The incidence of MS is also elevated in northern climates, where vitamin D deficiency is common. Since exposure of the skin to ultraviolet light aids in the conversion of inactive vitamin D to the active form, the short days, low UV intensity, and lack of exposed skin common to winter months, decrease the amount of active VitD3 that can be produced. Although the correlation between VitD3 deficiency and MS is intriguing, we are only now beginning to understand the biology that may explain this connection. In both human MS and in experimental autoimmune encephalomyelitis (EAE), the mouse model of the disease, VitD3 can influence specialized populations of cells that may play a critical role in protection against the disease. VitD3 promotes the formation of tolerogenic or “semi-mature” dendritic cells (DCs). These DCs induce the development of CD25–FoxP3+/–IL-10++ Tr1 cells, a subset of regulatory T cells (Treg), and downregulate the production of Th1 inflammatory cells. A pair of interacting co-inhibitory proteins, B7-H1 (also known as PD-L1) and PD-1, appear to be critical molecules in this process.
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Junge Diabetiker häufig mit Viren infiziert
2010-05-25 01:01 (0 Kommentare)
scienceticker.info:
Zumindest einige Fälle von Autoimmundiabetes könnten durch Virusinfektionen ausgelöst werden. Neue Indizien für einen solchen Mechanismus haben italienische Forscher im Rahmen einer kleinen Studie mit 112 jungen Patienten gefunden. Von diesen wiesen 83 Prozent zum Zeitpunkt der Diabetesdiagnose Zeichen einer Infektion mit Enteroviren auf. In einer gleichaltrigen Kontrollgruppe lag der Anteil dagegen nur bei 7 Prozent.
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Wenn das Immunsystem auf die Psyche schlägt - Vielfältiges Miteinander von Nervensystem und Körperabwehr
2010-05-19 19:30 (0 Kommentare)
nzz.ch:
Das Nerven- und das Immunsystem stehen über Botenstoffe in regem Austausch miteinander. Wird diese Kommunikation gestört, ist mit vielfältigen Problemen zu rechnen.
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An Immune Response in a Test Tube
2010-04-17 01:05 (0 Kommentare)
hhmi.org:
This work uncovers a fundamental mechanism of immune defense against many forms of viral infection – influenza, hepatitis, SARS, West Nile, and others.
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